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-----I stayed up late last night preparing the speech.
-----__________ you look so tired today.

-- How long do you think it will be ______ the bus arrives here?
-- No more than five minutes.

__________ that these creatures are linked to a common ancestor.

There is no ____ that 100 years ago animal testing was cruel, but today animals in experiments are very well taken care of.

– Do you know the West Lake in Hangzhou?
– Yes, this is the third time that I ____ this beautiful city.

—Can you describe _____ it happened?
　　—Yes, I was riding on my bike _____ a car knocked me down from behind.

They told us it was the second time that the volunteers _______ the nursing home.

There is no _______ that drinking milk before going to bed is helpful to our health.