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She looks sad. Could you please tell me ____ that prevents her from being as happy as before?
A．what it isB．it is whatC．how it isD．it is how
A
本題含有強(qiáng)調(diào)句型，若把It is···that去掉，則很容易地看出what引導(dǎo)的賓語(yǔ)從句，what在從句中充當(dāng)主語(yǔ)。故選A。
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